Synopsis
Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.
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Cast
- Adrien BrodyClive
- Sarah PolleyElsa
- Delphine ChanéacDren
- David HewlettBarlow
- Abigail ChuYoung Dren
- Stephanie BairdElsa / PD
- Brandon McGibbonGavin
- Amanda BrugelMelinda Finch
- Simona MăicănescuJoan Chorot
- 91
Entertainment Weekly
A cheeky, great-looking, thoughtfully loopy creature feature about the lure and dangers of cutting-edge gene splicing. - 91
Tampa Bay Times
It's a refreshing change from run-of-the-kill horror. Nothing in Splice feels done merely for the moment -- it's to creep you out later. - 70
The Hollywood Reporter
Writer/director Vincenzo Natali takes his tale in some truly icky directions, not quite making it into Cronenbergland but going far enough to elicit solid 'ewww' laughs from the crowd. - 70
Variety
Vincenzo Natali's outlandish sci-fier sustains a grotesque and funny fascination throughout its slightly protracted runtime. - 70
Village Voice
Splice is a queerly funny movie, attuned to the absurd. - 67
Austin Chronicle
Splice is a twisted little genetic updating that's not half as electrifying as Shelley's novel twist on the whole man/God/creation situation (and the perils thereof). - 63
ReelViews
Splice is as much a psychological thriller and drama about bio-ethics as it is a horror movie. Like the vastly superior "The Fly," it uses gore sparingly; delivering shocks to the audience is a secondary consideration. - 60
Time Out
If you’ve seen "Species," you know where this don’t-mess-with-Mother-Nature horror show is going, though director-cowriter Vincenzo Natali has a few interesting twists up his sleeve.